The SystemWeaver server application can be run in virtualized server environments like VMware (of VMware Inc.). However, such environments may not be intended or optimized for in-memory databases, and as a result performance may be less-than optimal*. It is recommended that you consult Systemite before deploying production environments in virtualized environments.
See SystemWeaver Server - Software and Hardware Requirements.
* It has been observed that virtualized environments do not always respect reserved RAM quota, which may severely deteriorate performance.